Key Takeaways Lipedema and Ehlers-Danlos syndrome often co-occur and have connective tissue abnormalities that can overlap, making diagnosis challenging and necessitating clinicians to consider both conditions together. Common symptoms include chronic pain, easy bruising, swelling and joint hypermobility. Gauge symptom trends to differentiate lipedema fat disbursement from simple obesity and fluid retention. Connective tissue laxity […]